metaEvidence - study list


	Study	study type RCT OBS RCT + OBS	Pathology	T1	T0	Patients	sample sizes	ROB	Results
non squamous - mNSCLC - L2 - all population metastatic/advanced NSCLC (mNSCLC) - 2nd line (L2) non squamous cell - mNSCLC - L2 non squamous - mNSCLC - L2 - all population
versus docetaxel
	nivolumab alone
	CheckMate 057, 2015 N Engl J Med 2015;373:1627-39 Eur. J. Cancer 2018; 102:23-30 J. Clin. Oncol. 2017; 35:3924-3933 J Clin Oncol 2021 Mar 1;39(7):723-733. NCT01673867	RCT	non squamous - mNSCLC - L2 - all population	nivolumab	docetaxel	Patients with advanced (stage IIIb or IV or recurrent) nonsquamous NSCLC that had progressed during or after platinum-based chemotherapy	292 / 290	some concern	conclusif	demonstrated 27 % decrease in deaths (OS) (PE) demonstrated 70 % increase in objective responses (ORR) (PE)