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Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID 19 outpatients meta-analysis

PRINCIPLE
 
ISRCTN86534580
RCTbudesonidestandard of careCOVID 19 outpatientssome concern
1073/1988 conclusif
  • demonstrated 21 % increase in clinical improvement,recovery (PE) with a moderate degree of certainty due to some concern in risk of bias
STOIC
 
NCT04416399
RCTbudesonidestandard of careCOVID 19 outpatientshigh
73/73 conclusif
  • demonstrated 84 % decrease in clinical deterioration (PE) but with a low degree of certainty due to high risk of bias

PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).