Table Graph
      published meta-analysis   sensitivity analysis   studies

convalescent plasma treatment in COVID-19 severe or critically - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsO’Donnell, 2021 0.47 [0.21; 1.06] PlasmAr, 2020 0.93 [0.47; 1.85] 0.68[0.35; 1.33]O’Donnell, 2021, PlasmAr, 2020237%556lownot evaluable deathsdetailed resultsO’Donnell, 2021 0.47 [0.21; 1.06] PlasmAr, 2020 0.93 [0.47; 1.85] 0.68[0.35; 1.33]O’Donnell, 2021, PlasmAr, 2020237%557lownot evaluable deaths (time to event analysis only)detailed resultsPlasmAr, 2020 0.93 [0.47; 1.85] 0.93[0.47; 1.85]PlasmAr, 202010%334NAnot evaluable clinical improvementdetailed resultsO’Donnell, 2021 1.20 [0.87; 1.65] PlasmAr, 2020 0.81 [0.50; 1.31] 1.03[0.71; 1.50]O’Donnell, 2021, PlasmAr, 2020244%556lownot evaluable clinical improvement (28-day)detailed resultsO’Donnell, 2021 1.38 [0.73; 2.61] 1.38[0.73; 2.61]O’Donnell, 202110%223NAnot evaluable clinical improvement (time to event analysis only)detailed resultsO’Donnell, 2021 1.20 [0.87; 1.65] PlasmAr, 2020 1.00 [0.76; 1.32] 1.08[0.88; 1.33]O’Donnell, 2021, PlasmAr, 202020%557lownot evaluable mechanical ventilationdetailed resultsO’Donnell, 2021 1.50 [0.47; 4.82] PlasmAr, 2020 0.86 [0.39; 1.93] 1.03[0.53; 2.00]O’Donnell, 2021, PlasmAr, 202020%556lownot evaluable serious adverse eventsdetailed resultsO’Donnell, 2021 0.64 [0.35; 1.17] PlasmAr, 2020 1.40 [0.78; 2.51] 0.95[0.44; 2.05]O’Donnell, 2021, PlasmAr, 2020270%552lownot evaluable0.52.01.0relative treatment effectwww.metaEvidence.org2024-04-28 10:14 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 91 - treatments: 538,957 - roots T: 290

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