All patients
adolescents (typically 12-15 years of age) adults (typically between 18 and 65yr) age >= 55 yr age >= 60 yr age >= 65 yr age >= 75 yr alpha variant (B.1.1.7, UK) any cancer autoimmune disease beta variant (B.1.351 / 501Y.V2, South Africa) children corticosteroids: no corticosteroids: yes critical disease delta variant (B.1.617.2, Indian) dialysis patients elderly (typically over 65yr) fully vaccinated gamma variant (P.1, Brazil) haematological cancers healthcare workers immunodepression invasive ventilation kidney transplant recipients no oxygen needed non invasive oxygen obese omicron variant BA.1 (B.1.1.529) omicron variant BA.2 VOC original (Wuhan) strain positive for SARS-Cov-2 at baseline severe disease solid cancer solid organ transplant recipients subjects at risk
potential COVID-19 treatments in COVID 19 hospitalized - Summary of results Outcome TE 95% CI n k I2 ROB Pub. bias death D28detailed results Zhang, 2020 0.50 [0.17; 1.50]
0.50 [0.17 ; 1.50 ] Zhang, 2020 1 0% 56 NA not evaluable deathsdetailed results Cao, 2020 0.15 [0.01; 3.29]
Entrenas (Pilot Calcifediol), 2020 0.12 [0.01; 2.79]
Murai, 2020 1.53 [0.53; 4.43]
Zhang, 2020 0.50 [0.17; 1.50]
0.62 [0.23 ; 1.71 ] Cao, 2020, Entrenas (Pilot Calcifediol), 2020, Murai, 2020, Zhang, 2020 4 34% 410 moderate not evaluable deaths (time to event analysis only)detailed results Zhang, 2020 0.50 [0.17; 1.50]
0.50 [0.17 ; 1.50 ] Zhang, 2020 1 0% 56 NA not evaluable clinical deteriorationdetailed results Cao, 2020 0.11 [0.01; 2.21]
Zhang, 2020 0.87 [0.23; 3.27]
0.49 [0.08 ; 3.03 ] Cao, 2020, Zhang, 2020 2 35% 97 moderate not evaluable clinical improvementdetailed results Cao, 2020 1.67 [0.84; 3.33]
1.67 [0.84 ; 3.33 ] Cao, 2020 1 0% 42 NA not evaluable clinical improvement (14-day)detailed results Cao, 2020 2.00 [0.58; 6.94]
2.00 [0.58 ; 6.94 ] Cao, 2020 1 0% 41 NA not evaluable clinical improvement (21-day)detailed results Cao, 2020 1.50 [0.22; 10.08]
1.50 [0.22 ; 10.08 ] Cao, 2020 1 0% 41 NA not evaluable clinical improvement (7-day)detailed results Cao, 2020 2.38 [0.38; 14.70]
2.38 [0.38 ; 14.70 ] Cao, 2020 1 0% 41 NA not evaluable clinical improvement (time to event analysis only)detailed results Cao, 2020 1.67 [0.84; 3.33]
1.67 [0.84 ; 3.33 ] Cao, 2020 1 0% 42 NA not evaluable hospital dischargedetailed results Murai, 2020 0.99 [0.71; 1.38]
0.99 [0.71 ; 1.38 ] Murai, 2020 1 0% 240 NA not evaluable mechanical ventilationdetailed results Murai, 2020 0.49 [0.21; 1.14]
0.49 [0.21 ; 1.14 ] Murai, 2020 1 0% 237 NA not evaluable radiologic improvement (14-day)detailed results Cao, 2020 5.54 [1.01; 30.50]
5.54 [1.01 ; 30.50 ] Cao, 2020 1 0% 41 NA not evaluable ICU admissiondetailed results Entrenas (Pilot Calcifediol), 2020 0.03 [0.00; 0.27]
Murai, 2020 0.71 [0.37; 1.37]
0.17 [0.01 ; 3.79 ] Entrenas (Pilot Calcifediol), 2020, Murai, 2020 2 86% 313 moderate not evaluable serious adverse eventsdetailed results Cao, 2020 0.11 [0.01; 2.21]
Murai, 2020 0.99 [0.02; 50.39]
0.25 [0.02 ; 2.69 ] Cao, 2020, Murai, 2020 2 0% 278 moderate not evaluable adverse eventsdetailed results Cao, 2020 1.60 [0.38; 6.81]
Murai, 2020 1.99 [0.07; 59.94]
1.65 [0.44 ; 6.27 ] Cao, 2020, Murai, 2020 2 0% 278 moderate not evaluable 0.0 10.0 1.0 relative treatment effect www.metaEvidence.org 2024-05-10 08:27 +02:00
TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers);
k: number of studies; n: total number of patients;
ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
pathologies: 95,94,90,91
- treatments: 290,547,608,830,831,829,901,680,595,828,681,1209,833,629,689,543,617,625,859,511,960,546,564,944,682,1266,943,894,560,1102,598,563,668,753,752,836,639,541,534,581,615,679,522,582,666,1149,1150,737,544,733,597,524,611,538,957,958,521,566,517,881,904,882,897,896,899,1235,898,687,740,883,947,536,591,729,887,742,878,975,570,771,888,1141,690,880,1255,567,596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526,616,926,1246,726,580,568,527,588,539,585,691,1210,525,843,827,1047,1048,819,545,1253,519,619,537,514,688,529,508,656,657,832,530,512,515,754,1142,1419,513,884,632,559,889,956,684,886,631,574,509,542,1145,555,554,941,961,1250,633,676,518,532,510,528,520,955,815,893,623,622,630,593,569,516,814,649,650,589,651,968,1245,610,751,747,695,548,970,594,565,879,1257,571,626,697,572,1234,586,573,540,592,930,949,838,698,934,735,929,948,946,945,587,655,1146,531,933,613,919,725,678,921,621,959,748,1348,1256,924,1243,925,658,699,612,552,590,891,605,892,722,618,609,551,834,763,922,935,620,1317,1265,824,766,857,1291,1088,1331,1330,1329,1344,1328,1327,979,822,762,805,950,757,761,806,758,826,755,821,1288,1287,1286,760,1284,802,765,1285,759,823,804,1264,764,858,835,1262,1290,1316,1341,1342,1343,825,803,1244,523,885,734,1439
- roots T: 290
