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ivermectin (n=100) vs. placebo (n=-9)
randomized controlled trial
ivermectin
12-15mg/ day for 3 days
placebo
COVID-19 (hospitalized or not)
double blind
1 center, Israel
zinc (n=96) vs. standard of care (n=95)
randomized controlled trial
Zinc and hydroxychloroquine.
Hydroxychloroquine at dose of 400 mg twice daily on the first day, then 200 mg twice daily for 5 days. Zinc in a dose of zinc sulfate 220 mg (50 mg of elemental zinc) twice daily.
Hydroxychloroquine only.
400 mg twice daily on the first day, then 200 mg twice daily for 5 days.
Both groups received the standard of care treatment for COVID-19 infection, according to the Egyptian Ministry of Health guidelines for 15 days.
COVID-19 (hospitalized or not)
All the included patients were classified into mild, moderate, severe, and critical according to the WHO case severity classification for COVID-19 infection.
Open-label
Multicenter, three major University hospitals in Cairo, Egypt.
group 1: both HCQ and zinc, group 2: HCQ only.
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