chloroquine and derivatives living meta-analysis of clinical studies

demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only

	COVID 19 all comers	COVID-19 mild to moderate	COVID-19 severe or critically

	COVID 19 hospitalized	COVID 19 all comers	COVID-19 mild to moderate	COVID-19 severe or critically
chloroquine and derivatives
chloroquine	Huang	Chen, ChiCTR2000030054 - Chloroquine	NCT04342650
hydroxychloroquine	RECOVERY Duke university HCQ HYCOVID ARCHAIC -hydroxychloroquine Gonzalez ... SOLIDARITY ... Abd-Elsalam PROTECT A HAHPS PROTECT B ORCHID TEACH Duke University hydroxychloroquine/azithromycine Chen OAHU-COVID19 Tang NO COVID-19 ... CCAP-1 IRCT20200428047228N1 // U07	ChiCTR2000030054-HCQ ... IRCT20150808023559N20 IRCT20150808023559N20 NOR-Solidarity ...	Zhaowei Chen Dubee Coalition Covid-19 Brazil I ... NCT04333654 Kamran HC-nCoV ... FACCT Trial	HYDRA ... Sarhan REMAP-CAP-HCQ Sarhan

4887	Gautret et al., 2020	1	31	3		not a RCT	high risk of bias
4905	ChiCTR2000029975, 0	2	30	0	excluded	not a RCT	risk of bias not avaialble
5056	Lopez, 2020	0	13	0	selection pending
5267	Mahevas, 2020	1	13	3		not a RCT	high risk of bias
5287	Chen_chloroquine, 2020	1	13	4		not a RCT	high risk of bias
5288	Barbosa, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
5313	Magagnoli (HC), 2020	1	13	3		not a RCT	high risk of bias
5350	Yu, 2020	1	13	4		not a RCT	high risk of bias
5351	Mallat, 2020	2	13	0	excluded	not a RCT	risk of bias not avaialble
5354	Geleris, 2020	1	13	3		not a RCT	high risk of bias
5365	Rosenberg, 2020	1	13	3		not a RCT	high risk of bias
5367	Huang, 2020	1	13	4		not a RCT	high risk of bias
5368	Novales, 2020	1	13	4		not a RCT	high risk of bias
5375	Mehra, 2020	2	13	3	excluded	not a RCT	high risk of bias
5478	Paccoud, 2020	1	13	3		not a RCT	high risk of bias
5481	Sbidian (HCQ alone), 2020	1	13	4		not a RCT	high risk of bias
5512	Arshad (HCQ), 2020	1	13	4		not a RCT	high risk of bias
5517	Min, 2020	1	13	0		not a RCT	risk of bias not avaialble
5596	Kalligeros, 2020	0	13	0	selection pending
5599	Karolyi, 2020	0	13	0	selection pending
5762	Belgian Collaborative Group on COVID-19, 2020	1	13	3		not a RCT	high risk of bias
5778	Cravedi, 2020	0	13	0	selection pending
5780	Fontana, 2020	0	13	0	selection pending
5789	Singh, 2020	1	13	4		not a RCT	high risk of bias
6252	NCT04376814-Group A, 2020	0	31	0	selection pending