Network meta-analysis for deaths_(OS)

Network meta-analysis estimations pool direct and indirect evidences. These results should be considered as exploratory given the absence of assessment of transitivity assumption plausibility. Calculations by netmeta package.

Evidence network for deaths_(OS)

1DETERMINE, 20171CONFIRM, 0nivolumab alone vs. placebo nivolumab alone better 0.72 [0.55; 0.94]0.72 [0.55;0.94]nivolumab alone vs. placebo nivolumab alone better 0.72 [0.55; 0.94]nivolumab alone vs. tremelimumab 0.78 [0.56; 1.09]0.78 [0.56;1.09]nivolumab alone vs. tremelimumab 0.78 [0.56; 1.09]placebo vs. nivolumab alone nivolumab alone better 1.39 [1.06; 1.82]1.39 [1.06;1.82]placebo vs. nivolumab alone nivolumab alone better 1.39 [1.06; 1.82]placebo vs. tremelimumab 1.09 [0.90; 1.32]1.09 [0.90;1.32]placebo vs. tremelimumab 1.09 [0.90; 1.32]tremelimumab vs. nivolumab alone 1.28 [0.92; 1.78]1.28 [0.92;1.78]tremelimumab vs. nivolumab alone 1.28 [0.92; 1.78]tremelimumab vs. placebo 0.92 [0.76; 1.12]0.92 [0.76;1.12]tremelimumab vs. placebo 0.92 [0.76; 1.12]placebotremelimumabnivolumab alonedirect evidencenetwork meta-analysis
T vs. C placebotremelimumabnivolumab alone
placebo---1.09
0.90; 1.32		1.39
1.06; 1.82
tremelimumab0.92
0.76; 1.12		---1.28
0.92; 1.78
nivolumab alone0.72
0.55; 0.94		0.78
0.56; 1.09		---

pathologies: 221 - treatments: 360,719,721,720 result logic

 

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