published meta-analysis   sensitivity analysis   studies

anticoagulant, prophylactic dose in COVID-19 severe or critically - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsCOVID-PACT, 2022 (REV) 1.10 [0.68; 1.79] INSPIRATION, 2021 (REV) 0.92 [0.66; 1.28] REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV) 0.92 [0.72; 1.18] 0.95[0.79; 1.14]COVID-PACT, 2022 (REV), INSPIRATION, 2021 (REV), REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV)30%2,042moderatenot evaluable clinical improvementdetailed resultsREMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV) 1.20 [0.97; 1.49] 1.20[0.97; 1.49]REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV)10%1,074NAnot evaluable Major thrombotic events or deathdetailed resultsCOVID-PACT, 2022 (REV) 1.79 [1.02; 3.14] REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV) 0.96 [0.74; 1.26] 1.24[0.68; 2.26]COVID-PACT, 2022 (REV), REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV)273%1,473moderatenot evaluable Major bleedingdetailed resultsCOVID-PACT, 2022 (REV) 0.26 [0.03; 2.29] INSPIRATION, 2021 (REV) 0.55 [0.16; 1.88] REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV) 0.68 [0.34; 1.36] 0.60[0.33; 1.08]COVID-PACT, 2022 (REV), INSPIRATION, 2021 (REV), REMAP-CAP, ACTIV-4a, ATTACC (critically ill patients), 2021 (REV)30%2,035moderatenot evaluable Thromboembolic eventsdetailed resultsINSPIRATION, 2021 (REV) 0.94 [0.67; 1.31] 0.94[0.67; 1.31]INSPIRATION, 2021 (REV)10%562NAnot evaluable0.22.01.0relative treatment effectwww.metaEvidence.org2024-05-03 16:52 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 91 - treatments: 829 - roots T: 290