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standard of care in COVID-19 mild to moderate - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsFACCT Trial, 2021 (REV) 1.44 [0.59; 3.51] 1.44[0.59; 3.51]FACCT Trial, 2021 (REV)10%254NAnot evaluable deathsdetailed resultsCoalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV) 0.68 [0.22; 2.09] FACCT Trial, 2021 (REV) 1.04 [0.48; 2.26] 0.91[0.48; 1.72]Coalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV), FACCT Trial, 2021 (REV)20%586moderatenot evaluable clinical deteriorationdetailed resultsCoalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV) 0.83 [0.47; 1.45] 0.83[0.47; 1.45]Coalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV)10%332NAnot evaluable clinical improvement (14-day)detailed resultsCoalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV) 1.21 [0.69; 2.12] 1.21[0.69; 2.12]Coalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV)10%448NAnot evaluable clinical improvement (time to event analysis only)detailed resultsFACCT Trial, 2021 (REV) 1.18 [0.86; 1.62] 1.18[0.86; 1.62]FACCT Trial, 2021 (REV)10%254NAnot evaluable hospital dischargedetailed resultsFACCT Trial, 2021 (REV) 1.14 [0.83; 1.57] 1.14[0.83; 1.57]FACCT Trial, 2021 (REV)10%254NAnot evaluable ICU admissiondetailed resultsFACCT Trial, 2021 (REV) 0.70 [0.39; 1.26] 0.70[0.39; 1.26]FACCT Trial, 2021 (REV)10%254NAnot evaluable adverse eventsdetailed resultsCoalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV) 1.14 [0.38; 3.42] 1.14[0.38; 3.42]Coalition Covid-19 Brazil I (Cavalcanti)-Hydroxychloroquine, 2020 (REV)10%332NAnot evaluable0.52.01.0relative treatment effectwww.metaEvidence.org2024-05-11 13:18 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 90 - treatments: 651 - roots T: 651