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standard of care in COVID 19 outpatients - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsPRINCIPLE, 2021 (REV) 0.61 [0.01; 30.66] 0.61[0.01; 30.66]PRINCIPLE, 2021 (REV)10%1,323NAnot evaluable hospitalization or deathdetailed resultsHinks (ATOMIC2), 2021 (REV) 1.10 [0.52; 2.32] 1.10[0.52; 2.32]Hinks (ATOMIC2), 2021 (REV)10%292NAnot evaluable A EFFACER PCR-negative (end of follow-up)detailed resultsHinks (ATOMIC2), 2021 (REV) 1.10 [0.69; 1.76] 1.10[0.69; 1.76]Hinks (ATOMIC2), 2021 (REV)10%295NAnot evaluable clinical improvementdetailed resultsPRINCIPLE, 2021 (REV) 0.93 [0.81; 1.05] 0.93[0.81; 1.05]PRINCIPLE, 2021 (REV)10%1,323NAnot evaluable clinical improvement (time to event analysis only)detailed resultsPRINCIPLE, 2021 (REV) 0.93 [0.81; 1.05] 0.93[0.81; 1.05]PRINCIPLE, 2021 (REV)10%1,323NAnot evaluable hospitalizationdetailed resultsHinks (ATOMIC2), 2021 (REV) 1.05 [0.51; 2.17] PRINCIPLE, 2021 (REV) 1.07 [0.57; 1.99] 1.06[0.66; 1.70]Hinks (ATOMIC2), 2021 (REV), PRINCIPLE, 2021 (REV)20%1,618moderatenot evaluable mechanical ventilationdetailed resultsPRINCIPLE, 2021 (REV) 1.99 [0.38; 10.31] 1.99[0.38; 10.31]PRINCIPLE, 2021 (REV)10%1,121NAnot evaluable ICU admissiondetailed resultsPRINCIPLE, 2021 (REV) 1.32 [0.31; 5.56] 1.32[0.31; 5.56]PRINCIPLE, 2021 (REV)10%1,120NAnot evaluable0.25.01.0relative treatment effectwww.metaEvidence.org2024-05-15 01:25 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 97 - treatments: 651 - roots T: 651

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