published meta-analysis   sensitivity analysis   studies

Immunosuppressants drugs in COVID-19 mild to moderate - Summary of results

OutcomeTE95% CInkI2ROBPub. bias death D28detailed resultsCAN-COVID, 2020 0.67 [0.30; 1.50] CORIMUNO-ANA-1, 2021 0.91 [0.38; 2.19] 0.77[0.43; 1.40]CAN-COVID, 2020, CORIMUNO-ANA-1, 202120%559moderatenot evaluable deathsdetailed resultsCAN-COVID, 2020 0.67 [0.30; 1.50] CORIMUNO-ANA-1, 2021 0.97 [0.46; 2.04] LIVE-AIR (Temesgen), 2021 0.70 [0.40; 1.21] SAVE-MORE, 2021 0.45 [0.20; 0.99] 0.68[0.48; 0.97]CAN-COVID, 2020, CORIMUNO-ANA-1, 2021, LIVE-AIR (Temesgen), 2021, SAVE-MORE, 202140%1,632moderatenot evaluable deaths (time to event analysis only)detailed resultsLIVE-AIR (Temesgen), 2021 0.70 [0.40; 1.21] 0.70[0.40; 1.21]LIVE-AIR (Temesgen), 202110%479NAnot evaluable clinical deteriorationdetailed resultsCORIMUNO-ANA-1, 2021 0.89 [0.42; 1.92] SAVE-MORE, 2021 0.36 [0.26; 0.50] 0.53[0.22; 1.28]CORIMUNO-ANA-1, 2021, SAVE-MORE, 2021278%114lownot evaluable clinical improvementdetailed resultsCAN-COVID, 2020 1.39 [0.76; 2.54] 1.39[0.76; 2.54]CAN-COVID, 202010%446NAnot evaluable death or ventilationdetailed resultsCORIMUNO-ANA-1, 2021 0.97 [0.62; 1.52] LIVE-AIR (Temesgen), 2021 0.65 [0.43; 0.98] 0.79[0.53; 1.16]CORIMUNO-ANA-1, 2021, LIVE-AIR (Temesgen), 2021240%116moderatenot evaluable mechanical ventilationdetailed resultsSAVE-MORE, 2021 0.47 [0.03; 7.48] 0.47[0.03; 7.48]SAVE-MORE, 202110%594NAnot evaluable serious adverse eventsdetailed resultsCAN-COVID, 2020 0.73 [0.45; 1.19] 0.73[0.45; 1.19]CAN-COVID, 202010%448NAnot evaluable0.22.01.0relative treatment effectwww.metaEvidence.org2024-04-16 21:45 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 90 - treatments: 596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526 - roots T: 290