published meta-analysis   sensitivity analysis   studies

potential COVID-19 treatments in COVID-19 severe or critically - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsCao, 2020 0.71 [0.36; 1.40] REMAP-CAP (lopinavir/ritonavir only), 2020 0.83 [0.65; 1.06] 0.81[0.65; 1.03]Cao, 2020, REMAP-CAP (lopinavir/ritonavir only), 202020%844moderatenot evaluable deaths (time to event analysis only)detailed resultsREMAP-CAP (lopinavir/ritonavir only), 2020 0.83 [0.65; 1.06] 0.83[0.65; 1.06]REMAP-CAP (lopinavir/ritonavir only), 202010%645NAnot evaluable clinical improvementdetailed resultsCao, 2020 1.31 [0.94; 1.83] 1.31[0.94; 1.83]Cao, 202010%NAnot evaluable clinical improvement (14-day)detailed resultsCao, 2020 1.94 [1.09; 3.48] REMAP-CAP (lopinavir/ritonavir only), 2020 0.85 [0.64; 1.12] 1.23[0.55; 2.76]Cao, 2020, REMAP-CAP (lopinavir/ritonavir only), 2020284%844moderatenot evaluable clinical improvement (28-day)detailed resultsCao, 2020 1.59 [0.84; 3.03] 1.59[0.84; 3.03]Cao, 202010%199NAnot evaluable clinical improvement (7-day)detailed resultsCao, 2020 3.16 [0.62; 16.06] 3.16[0.62; 16.06]Cao, 202010%199NAnot evaluable clinical improvement (time to event analysis only)detailed resultsCao, 2020 1.31 [0.94; 1.83] 1.31[0.94; 1.83]Cao, 202010%NAnot evaluable hospital dischargedetailed resultsREMAP-CAP (lopinavir/ritonavir only), 2020 0.83 [0.69; 1.00] 0.83[0.69; 1.00]REMAP-CAP (lopinavir/ritonavir only), 202010%645NAnot evaluable serious adverse eventsdetailed resultsCao, 2020 0.52 [0.27; 1.01] REMAP-CAP (lopinavir/ritonavir only), 2020 1.57 [0.70; 3.49] 0.88[0.30; 2.58]Cao, 2020, REMAP-CAP (lopinavir/ritonavir only), 2020277%811moderatenot evaluable0.55.01.0relative treatment effectwww.metaEvidence.org2024-05-11 06:09 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 91 - treatments: 290,547,608,830,831,829,901,680,595,828,681,1209,833,629,689,543,617,625,859,511,960,546,564,944,682,1266,943,894,560,1102,598,563,668,753,752,836,639,541,534,581,615,679,522,582,666,1149,1150,737,544,733,597,524,611,538,957,958,521,566,517,881,904,882,897,896,899,1235,898,687,740,883,947,536,591,729,887,742,878,975,570,771,888,1141,690,880,1255,567,596,1437,600,652,557,635,1236,553,628,646,645,607,395,920,1438,927,932,931,1263,599,614,942,1436,928,923,535,1046,727,818,606,954,964,962,963,1045,638,677,627,533,526,616,926,1246,726,580,568,527,588,539,585,691,1210,525,843,827,1047,1048,819,545,1253,519,619,537,514,688,529,508,656,657,832,530,512,515,754,1142,1419,513,884,632,559,889,956,684,886,631,574,509,542,1145,555,554,941,961,1250,633,676,518,532,510,528,520,955,815,893,623,622,630,593,569,516,814,649,650,589,651,968,1245,610,751,747,695,548,970,594,565,879,1257,571,626,697,572,1234,586,573,540,592,930,949,838,698,934,735,929,948,946,945,587,655,1146,531,933,613,919,725,678,921,621,959,748,1348,1256,924,1243,925,658,699,612,552,590,891,605,892,722,618,609,551,834,763,922,935,620,1317,1265,824,766,857,1291,1088,1331,1330,1329,1344,1328,1327,979,822,762,805,950,757,761,806,758,826,755,821,1288,1287,1286,760,1284,802,765,1285,759,823,804,1264,764,858,835,1262,1290,1316,1341,1342,1343,825,803,1244,523,885,734,1439 - roots T: 290