x1: number of event in experimental group (studied treatment); n1: sample size of experimental group;
x0: number of event in control group (control treatment); n0: sample size of control group;
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s);
Conclusive (statistically conclusive): statistically significant with a strict control of overall risk of type 1 error (statistically demonstrated), does not take into account the risk of bias;

Forest plot

hydroxychloroquine in COVID 19 outpatients

1: Mitja et al. Clin Infect Dis; 2: Amaravadi;

Sensitivity analysis

Bayesian posterior probability of treatment effect

Bayesian (posterior) relative TE 95% CI: 0.79 [0.34; 1.81]

posterior probability of favorable treatment effect (PTE): 71.3 %

some concern risk of bias. This probability should be interpreted according to the risk of bias.

Publication bias, Funnel plot

funnel plot

Funnel plot not drawn. Less than 3 points!

Asymetry test p-value = NaN (by Egger's regression)