metaEvidence - study list


	Study	study type RCT OBS RCT + OBS	Pathology	T1	T0	Patients	sample sizes	ROB	Results	deaths (OS) E	progression or deaths (PFS) E	RFS/DFS E
mNSCLC - L1 - PDL1 positive metastatic/advanced NSCLC (mNSCLC) - 1st line (L1) mNSCLC - L1 - PDL1 positive
versus Standard of Care (SoC)
	nivolumab alone
	CheckMate 026 (PDL1>5%), 2016 N Engl J Med 2017 Jun 22;376(25):2415-2426. NCT02041533	RCT	mNSCLC - L1 - PDL1 positive	Nivolumab	platinum-based chemotherapy	patients previously untreated had histologically confirmed squamous-cell or nonsquamous stage IV or recurrent NSCLC PD-L1 at >1%	211 / 212	some concern	inconclusive
	CheckMate 026 (PDL1>1%), 2016 N Engl J Med 2017 Jun 22;376(25):2415-2426. NCT02041533	RCT	mNSCLC - L1 - PDL1 positive	Nivolumab	platinium doublet chemotherapy	patients previously untreated had histologically confirmed squamous-cell or nonsquamous stage IV or recurrent NSCLC with PD-L1 >1%	271 / 270	some concern	inconclusive